Author contributions:
Ping Zhao:Data curation, Writing original draft, Writing
review & editing. Cuiping Liu, and Jian Wu designed the study and provided resources and fundings.Ping Zhao, YanHong Yang and Saizhe Song conducted the experiment, performed data analysis, and wrote the manuscript. Wei Cheng, Cheng Peng, and Xin Chang participated in the sample and clinical data collection. Jian Wu and Cuiping Liu helped optimize the research and proofread the paper and revised the manuscript. All authors helped the final approval of the version.
Acknowledgements: We sincerely thank the platform provided by Jiangsu Institute of Clinical Immunology & Jiangsu Key Laboratory of Clinical Immunology. We are grateful for the help provided by all department of rheumatology in the First Afffliated Hospital of Soochow University.
Data Availability Statement: The data sets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.