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Methodological assessment of Mexican Clinical Practice Guidelines: Critical appraisal and GRADE framework adherence.
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  • Luis Colunga-Lozano,
  • Vilma Gerardo-Morales,
  • Giordano Pérez-Gaxiola,
  • Alan Omar Vázquez-Alvarez,
  • Francisco Javier González-Torres ,
  • Leonardo Perales-Guerrero ,
  • Ekatherina Yanowsky-Ortega ,
  • Ulises I. Martínez-Tolentino,
  • Sergio J. Sánchez-Villaseca,
  • Luz Angélica García-Macías,
  • Robby Nieuwlaat,
  • Gordon Guyatt,
  • Ivan D. Florez
Luis Colunga-Lozano
Hospital Civil de Guadalajara Dr Juan I Menchaca
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Vilma Gerardo-Morales
Hospital Pediatrico de Sinaloa
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Giordano Pérez-Gaxiola
Hospital Pediatrico de Sinaloa
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Alan Omar Vázquez-Alvarez
Universidad de Guadalajara Centro Universitario de Ciencias de la Salud
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Francisco Javier González-Torres
Universidad de Guadalajara Centro Universitario de Ciencias de la Salud
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Leonardo Perales-Guerrero
Universidad de Guadalajara Centro Universitario de Ciencias de la Salud
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Ekatherina Yanowsky-Ortega
Universidad de Guadalajara Centro Universitario de Ciencias de la Salud
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Ulises I. Martínez-Tolentino
Universidad de Guadalajara Centro Universitario de Ciencias de la Salud
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Sergio J. Sánchez-Villaseca
Universidad de Guadalajara Centro Universitario de Ciencias de la Salud
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Luz Angélica García-Macías
Universidad de Guadalajara Centro Universitario de Ciencias de la Salud
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Robby Nieuwlaat
McMaster University
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Gordon Guyatt
McMaster University
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Ivan D. Florez
Universidad de Antioquia
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Abstract

Background and Objective Clinical Practice Guidelines (CPGs) provide evidence-based recommendations to healthcare professionals, policy makers, patients and other stakeholders. Mexico is the biggest producer of CPGs in Latin America and Caribbean countries. The National Healthcare Technology Excellence Center (acronym in Spanish: CENETEC) is responsible for the CPG development, adaptation and update. The aim of this study was to assess the Mexican CPG quality and adherence to the GRADE framework. Study design We conducted a descriptive cross-sectional study of 86 CPGs representing all the CPGs produced by CENETEC between 2015 and 2017 and published in an online database called “Catalogo Maestro”. We performed quality assessment with the online AGREE II tool and assessed the reporting on the GRADE framework. Results Of the 86 CPGs, 34 were published in 2015, 21 in 2016 and 31 in 2017. The overall quality by AGREE II proved a median of 16.6% (Min 16.6%, Max 50%). Of the 86 CPGs, 25 (29%) used the GRADE framework; adherence to GRADE standards was, however, inconsistent and generally poor. Conclusion CPGs produced by CENETEC during this period had a low score by AGREE II standards and low adherence to the GRADE framework. A concerted initiative could rapidly improve CENETEC guidelines.

Peer review status:ACCEPTED

03 Dec 2019Submitted to Journal of Evaluation in Clinical Practice
16 Jan 2020Submission Checks Completed
16 Jan 2020Assigned to Editor
20 Jan 2020Reviewer(s) Assigned
06 Apr 2020Review(s) Completed, Editorial Evaluation Pending
06 Apr 2020Editorial Decision: Revise Major
01 Jul 20201st Revision Received
01 Jul 2020Submission Checks Completed
01 Jul 2020Assigned to Editor
03 Jul 2020Review(s) Completed, Editorial Evaluation Pending
03 Jul 2020Editorial Decision: Accept