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Computational study on the influence of the location of the distal pressure measurement point in the Fractional Flow Reserve
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  • Rafael Agujetas-Ortiz,
  • Conrado Ferrera-Llera,
  • Reyes González-Fernández,
  • Juan Manuel Nogales-Asensio,
  • Ana Fernández-Tena
Rafael Agujetas-Ortiz
University of Extremadura
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Conrado Ferrera-Llera
University of Extremadura
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Reyes González-Fernández
University of Extremadura
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Juan Manuel Nogales-Asensio
University of Extremadura
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Ana Fernández-Tena
Instituto Nacional de Silicosis
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Abstract

Coronary stenosis is largely responsible of severe heart failure as they can stop the blood flow to the myocardial. The Fractional Flow Reserve (FFR) is the most usual functional assessment of the severity of the coronary stenosis. In most cases, its value dictates the clinical decision to set a stent to restore the flow. Therefore, a correct measurement of this variable is crucial. This information can be very important to prevent cardiologists from making the wrong clinical decisions. From the data taken from an anonymous patient who underwent Coronary Computed Tomographic Angiography and cardiac catheterization, a comparison was made with the results of a computational simulation of the model reconstructed from the angiography. The results of the Fractional Flow Reserve obtained by simulation (0.834) agree with those obtained experimentally (0.830), difference less than 0.8%, which indicates that with simulation it is possible to obtain results that would be very difficult to achieve experimentally. The actual invasive procedure to measure the Fractional Flow Reserve is being executed with a protocol that do not consider the influence of the location on the Pd value. The new procedure would avoid false results related to the point where the distal pressure is measured.