A physical psychological factor in immunostimulation activity and
homeostasis safeguarding
Abstract
Abstract The objective of our study is to propose a therapeutic strategy
based on the administration of cyclosporine alone, and cyclosporine
associated with a sound noise in two batches of animals treated with an
immunostimulant Biliated bacillus of Calmette and Guerin, all based on
the hypothesis of the central role of neuroimmuno-endocrine regulation
loop in disorders related to the administration of cyclosporine. We
administered cyclosporine alone (IP) for 8 days, as well as
administration of cyclosporine associated with sound noise with food and
sugar water and stained in two batches of Biliated bacillus of Calmette
and Guerin -treated animals ( in ID), the animals received Biliated
bacillus of Calmette and Guerin injections on the 9th day and a reminder
on the 27th day. Our results show that intraperitoneal injection of
cyclosporine alone (20 mg / kg) causes a significant decrease in
testosteronemia associated with a drop in body weight. Similar results
were found following administration of cyclosporine associated with
sound noise. Conversely, administration of cyclosporine alone and
associated with sound noise caused a significant increase in
adrenocorticotropic hormone. Indicating that sound noise mimics the
effect of cyclosporine in male rats. Keywords: Immunosuppression,
immunostimulation, psychotherapy, homeostasis