Background: This bibliometric analysis is used to identify publications
and highlights the key areas that have significantly shaped modern
clinical practice for aortic valve replacement (AVR), which is becoming
increasingly relevant. The top 100 most cited manuscripts for AVR were
analysed. Method: The Thomson Reuters Web of Science database was
searched using the terms ‘aortic valve replacement’, ‘replacement’,
‘aortic valve’ and/or ‘AVR’ for full manuscripts in English Language.
The results were ranked by citation number and the top 100 articles were
further analysed by subject, author, journal, year of publication,
institution and country of origin. Results: 26,782 eligible papers were
returned and accumulated 76,680 citations in total, with a mean citation
of 767 per manuscript (350-3667). The New England Journal of Medicine
accumulated the most citations whereas Circulation published the most
papers. Majority of manuscripts examined patients with aortic stenosis,
of which half also included aortic regurgitation. The United States of
America contributed 51 manuscripts, accumulating 43629 citations.
Conclusion: The most cited manuscript, by Leon et al., assessed the
outcomes of transcatheter aortic valve implantation in patients with
severe aortic stenosis who were unfit for surgical replacement. By
providing the most influential references this work serves as a guide to
topics of interest in the field of AVR.