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COVID-19-induced hypoxaemia: Focus on red blood cells
  • +3
  • Alireza Mani,
  • Keshvad Hedayatyanfard,
  • Razieh Mohammad Jafari,
  • Parsa Mohammadi,
  • Shahram Ejtemaei Mehr,
  • Ahmad Dehpour
Alireza Mani
UCL
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Keshvad Hedayatyanfard
Alborz University of Medical Sciences
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Razieh Mohammad Jafari
Tehran University of Medical Sciences
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Parsa Mohammadi
Tehran University of Medical Sciences
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Shahram Ejtemaei Mehr
Tehran University of Medical Sciences
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Ahmad Dehpour
Tehran University of Medical Sciences
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Abstract

Recent observations suggest that COVID-19 causes an “atypical” form of acute respiratory distress syndrome with impaired pulmonary circulation and enhanced thromboembolism. In this letter we have proposed that the interaction between erythrocytes and endothelial cells may have a crucial role in pathogenesis of COVID-19. Acknowledging this interaction suggests new targets for transnational research during the pandemic.