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Molecular and serological investigation of cat viral infectious diseases in China from 2016 to 2019
  • +10
  • Caihong Liu,
  • Yuxiu Liu ,
  • Peng Qian,
  • Yujiao Cao,
  • Jie Wang,
  • ChunYan Sun,
  • Baicheng Huang,
  • Ningning Cui,
  • Ningning Huo,
  • Hongchao Wu,
  • Lingxiao Wang,
  • Xiangfeng Xi,
  • Kegong Tian
Caihong Liu
National Research Center for Veterinary Medicine
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Yuxiu Liu
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Peng Qian
National Research Center for Veterinary Medicine
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Yujiao Cao
National Research Center for Veterinary Medicine
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Jie Wang
National Research Center for Veterinary Medicine
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ChunYan Sun
National Research Center for Veterinary Medicine
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Baicheng Huang
National Research Center for Veterinary Medicine
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Ningning Cui
National Research Center for Veterinary Medicine
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Ningning Huo
National Research Center for Veterinary Medicine
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Hongchao Wu
National Research Center for Veterinary Medicine
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Lingxiao Wang
National Research Center for Veterinary Medicine
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Xiangfeng Xi
National Research Center for Veterinary Medicine
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Kegong Tian
National Research Center for Veterinary Medicine
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Abstract

In order to analyze the prevalence of cat viral diseases in China, including feline parvovirus (FPV), feline calicivirus (FCV), feline herpesvirus-1 (FHV-1), feline leukemia virus (FeLV), feline immunodeficiency virus (FIV) and feline infectious peritonitis virus (FIPV), a total of 1,326 samples of cats from 16 cities were investigated from 2016 to 2019. Collectively, 1,060 (79.9%) cats were tested positive for at least one virus in nucleotide detection, the positive rates of cat exposure to FeLV, FPV, FHV-1, FCV, FIV and FIPV were 59.6%, 19.2%, 16.3%, 14.2%, 1.5% and 0.5%, respectively. The prevalence of FHV-1 and FPV were dominant in winter and spring. Cats from north China showed a higher positive rate of viral infection than that of cats from south China. The virus infection is not highly correlated with age, except that FPV is prone to occur within the age of 12 months. In the serological survey, the seroprevalences of 267 vaccinated cats to FPV, FCV, FHV-1 were 83.9%, 58.3% and 44.0%, respectively. Meanwhile, the seroprevalences of 39 unvaccinated cats to FPV, FCV, FHV-1 were 76.9% (30/39), 82.4% (28/34) and 58.6% (17/29), respectively. This study demonstrated that a high prevalence of the six viral diseases in China, and the insufficient serological potency of FCV and FHV reminds the urgency for more effective vaccines.

Peer review status:ACCEPTED

21 Apr 2020Submitted to Transboundary and Emerging Diseases
21 Apr 2020Submission Checks Completed
21 Apr 2020Assigned to Editor
26 Apr 2020Reviewer(s) Assigned
09 May 2020Review(s) Completed, Editorial Evaluation Pending
19 May 2020Editorial Decision: Revise Minor
21 May 20201st Revision Received
25 May 2020Submission Checks Completed
25 May 2020Assigned to Editor
31 May 2020Reviewer(s) Assigned
02 Jun 2020Review(s) Completed, Editorial Evaluation Pending
02 Jun 2020Editorial Decision: Accept