loading page

Pathological investigation and viral antigen distribution of emerging African Swine Fever in Vietnam
  • +7
  • Uda Zahli Izzati,
  • Minori Inanaga,
  • Nguyen Hoa,
  • Phawut Nueangphuet,
  • Ohnmar Myint,
  • Quang Lam Truong,
  • Thi Lan Nguyen,
  • Junzo Norimine,
  • Takuya Hirai,
  • Ryoji Yamaguchi
Uda Zahli Izzati
University of Miyazaki
Author Profile
Minori Inanaga
University of Miyazaki
Author Profile
Nguyen Hoa
Vietnam National University of Agriculture
Author Profile
Phawut Nueangphuet
University of Miyazaki
Author Profile
Ohnmar Myint
University of Miyazaki
Author Profile
Quang Lam Truong
Author Profile
Thi Lan Nguyen
Vietnam National University of Agriculture
Author Profile
Junzo Norimine
Author Profile
Takuya Hirai
Author Profile
Ryoji Yamaguchi
University of Miyazaki
Author Profile

Abstract

African swine fever (ASF) is emerging in Vietnam and poses a continuing severe threat to the swine industry. A histopathological study of clinical samples collected during the August to September 2019 outbreak of ASF was performed to determine the characteristic lesions. We analyzed samples from eight ASFV-infected farms. Histopathological results revealed the characteristic lesions of the acute to the subacute clinical form of ASF. Immunohistochemical results showed ASFV viral antigen distribution in mononuclear cells/macrophage in various organs, hepatocytes, and renal tubular epithelium. Molecular analysis of partial capsid protein 72 gene revealed that ASFV strain from the eight separate outbreaks belonged to genotype II.

Peer review status:ACCEPTED

27 Apr 2020Submitted to Transboundary and Emerging Diseases
27 Apr 2020Submission Checks Completed
27 Apr 2020Assigned to Editor
07 May 2020Reviewer(s) Assigned
19 Jun 2020Review(s) Completed, Editorial Evaluation Pending
19 Jun 2020Editorial Decision: Revise Minor
29 Jul 20201st Revision Received
30 Jul 2020Submission Checks Completed
30 Jul 2020Assigned to Editor
31 Jul 2020Reviewer(s) Assigned
17 Sep 2020Review(s) Completed, Editorial Evaluation Pending
18 Sep 2020Editorial Decision: Accept