loading page

Limited Efficacy and Adverse Effect of Sodium Hyaluronic Acid-Carboxymethylcellulose and Oxidized Regenerated Cellulose at Primary Cesarean Delivery
  • +2
  • Kuan-Sheng Lee,
  • Yeou-Lih Wang,
  • Wen-Chu Huang,
  • Jia-Hwa Yang,
  • Jian-Pei Huang
Kuan-Sheng Lee
Mackay Memorial Hospital
Author Profile
Yeou-Lih Wang
Mackay Memorial Hospital
Author Profile
Wen-Chu Huang
Mackay Memorial Hospital
Author Profile
Jia-Hwa Yang
Taipei Veterans General Hospital
Author Profile
Jian-Pei Huang
Mackay Memorial Hospital
Author Profile

Abstract

Introduction: Adhesion is associated to delayed delivery of the neonate and higher incidence of intraoperative and postoperative complications. Currently, there is no definite consensus regarding the use of adhesion barriers at cesarean section. Objective: To analyze the postoperative outcomes among two adhesion barrier groups and control group at the primary and the secondary cesarean section. Methods: This retrospective study includes 199 Asian women undergoing primary and secondary cesarean section between January1, 2011, and September 31, 2019. We used regression to analyze risk factors of postcesarean fever at primary cesarean section. Further we used interaction analysis to examine the effect of surgical site infection risk factors and use of adhesion barrier on postcesarean fever rates at the primary cesarean section. Results: We found that use of adhesion barrier at the primary cesarean section is associated with a significantly higher incidence of postcesarean fever (p=0.045). The risk factor for postcesarean fever is the use of anti-adhesion filmduring emergency cesarean section (p=0.041). In the subgroup of labor before operation and emergency cesarean section, adhesion barrier user had significant higher risk of postcesarean fever than nonuser (p<0.05). Conclusion: The patients used of anti-adhesion films during emergency cases and when a woman has labor before operation is associated with a significantly higher risk of postcesarean fever which potentially means increased risk of surgical site infection.