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SLEEP- DISORDERED BREATHING IN CYSTIC FIBROSIS
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  • AESHA JOBANPUTRA,
  • SUGEET JAGPAL,
  • OMAR AHMED,
  • TEODORO SANTIAGO,
  • MAYA RAMAGOPAL
AESHA JOBANPUTRA
Rutgers The State University of New Jersey
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SUGEET JAGPAL
Rutgers The State University of New Jersey
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OMAR AHMED
Rutgers The State University of New Jersey
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TEODORO SANTIAGO
Rutgers The State University of New Jersey
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MAYA RAMAGOPAL
Rutgers Robert Wood Johnson Medical School New Brunswick
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Abstract

Sleep-disordered breathing is an underrecognized comorbidity in the cystic fibrosis (CF) population across the lifespan. Nocturnal hypoxia, obstructive sleep apnea (OSA), and nocturnal hypoventilation are respiratory abnormalities that occur commonly during sleep, and have deleterious consequences to quality of life in people with CF. Effective screening for these abnormalities is needed to allow for the timely initiation of treatment. Lack of treatment leads to worse pulmonary, cardiovascular, and metabolic outcomes in patients. In this review, we give an overview of sleep-disordered breathing for the CF clinician, including definitions, treatment, and suggestions for future research. We strongly encourage the CF community to incorporate evaluation for sleep-disordered breathing, so that outcomes for the subset of the patients with coexisting sleep-disordered breathing improve.

Peer review status:ACCEPTED

15 May 2020Submitted to Pediatric Pulmonology
18 May 2020Submission Checks Completed
18 May 2020Assigned to Editor
19 May 2020Reviewer(s) Assigned
08 Jun 2020Review(s) Completed, Editorial Evaluation Pending
08 Jun 2020Editorial Decision: Revise Major
06 Jul 20201st Revision Received
06 Jul 2020Submission Checks Completed
06 Jul 2020Assigned to Editor
06 Jul 2020Reviewer(s) Assigned
08 Aug 2020Review(s) Completed, Editorial Evaluation Pending
08 Aug 2020Editorial Decision: Accept