loading page

Vitamin D Supplementation Could Potentially Reduce Risk of COVID-19 Infections and Deaths
  • Jing Qin Tay,
  • Ajay L Mahajan,
  • M Julie Thornton
Jing Qin Tay
Bradford Teaching Hospitals NHS Foundation Trust
Author Profile
Ajay L Mahajan
University of Bradford
Author Profile
M Julie Thornton
University of Bradford
Author Profile

Abstract

Vitamin D has long been known to be a major regulator for both the endocrine and the immune system. With the advent of COVID-19 pandemic, there has been a growing interest in looking at the feasibility of using vitamin D as a preventative and therapeutic option in the management of the disease. A low serum level of vitamin D is linked to higher incidence of respiratory tract infection and disease progression. Vitamin D supplementation has proven to be effective in enhancing the immune system, strengthen lung epithelial barrier, and prevention of unchecked inflammatory response. Previous studies on the roles of vitamin D in managing influenza and other enveloped virus infection could shed light on the possible roles of vitamin D in the current pandemic. More randomised controlled trials are needed to explore the effects of vitamin D supplementation on COVID-19 infection.

Peer review status:UNDER REVIEW

17 May 2020Submitted to International Journal of Clinical Practice
18 May 2020Assigned to Editor
18 May 2020Submission Checks Completed
26 May 2020Reviewer(s) Assigned
21 Oct 2020Review(s) Completed, Editorial Evaluation Pending