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Vitamin D Supplementation Could Potentially Reduce Risk of COVID-19 Infections and Deaths
  • Jing Qin Tay,
  • Ajay L Mahajan,
  • M Julie Thornton
Jing Qin Tay
Bradford Teaching Hospitals NHS Foundation Trust
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Ajay L Mahajan
University of Bradford
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M Julie Thornton
University of Bradford
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Abstract

Vitamin D has long been known to be a major regulator for both the endocrine and the immune system. With the advent of COVID-19 pandemic, there has been a growing interest in looking at the feasibility of using vitamin D as a preventative and therapeutic option in the management of the disease. A low serum level of vitamin D is linked to higher incidence of respiratory tract infection and disease progression. Vitamin D supplementation has proven to be effective in enhancing the immune system, strengthen lung epithelial barrier, and prevention of unchecked inflammatory response. Previous studies on the roles of vitamin D in managing influenza and other enveloped virus infection could shed light on the possible roles of vitamin D in the current pandemic. More randomised controlled trials are needed to explore the effects of vitamin D supplementation on COVID-19 infection.

Peer review status:UNDER REVIEW

17 May 2020Submitted to International Journal of Clinical Practice
18 May 2020Assigned to Editor
18 May 2020Submission Checks Completed
26 May 2020Reviewer(s) Assigned