Incidence of Infant Respiratory Disease can be Decreased by Vitamin A
Supplement: A system review and meta analyses
Abstract
Objective: To investigate whether vitamin A are associated with a lower
fracture incidence in infants’ respiratory system diseases. Method: A
systematic literature search of articles update to April 2020 was
conducted via PubMed, Web of Science, and the Chinese National Knowledge
Infrastructure (CNKI), Chinese biomedical literature database (CBM), and
the references of the retrieved articles. Fixed- or random-effect models
were used to summarize the estimates of OR with 95% CIs for the vitamin
A are associated with a lower fracture incidence in infants’ respiratory
system diseases. Result: This study includes 18 articles. Compared with
control group, the experimental group’s infant babies are less likely to
get poor health outcomes. Especially ,suffering from respiratory
related disease, such as,neonatal respiratory distress syndrome (NRDS)
(OR = 0.79), neonatal pneumonia (OR = 0.51), neonatal ALRI to acute
lower respiratory infection (OR = 0.66), neonatal bronchial pulmonary
hypoplasia bronchopulmonary dysplasia of premature infants (BPD)(OR =
0.49). All test of the difference had ensured statistical significance
(P < 0.05). Conclusion: This meta-analysis indicated that
Vitamin A intake was associated with a decreased risk of infants’
respiratory system related diseases. Further researches should be
conducted to confirm the findings in our study and better clarify the
potential biological mechanisms.