This study is the first to demonstrate an atypical porcine pestivirus
(APPV) HeN01 strain isolated from congenital tremor (CT) diseased
piglets in Henan, Central China, indicating that APPV has spread north
of the Yangtze River. The epidemiological monitoring of APPV and the
health management of livestock in northern China should be increased to
prevent outbreaks and animal loss. In addition, we successfully isolated
APPV to provide a material basis for the development of APPV vaccines.