Numb Chin Syndrome as a presentation for Acute Myeloid Leukemia Relapse
Post Hematopoietic Cell Transplant: Case Report and Review of Literature
Abstract
Numb chin syndrome (NCS) is defined as reduced or absent sensation in
the chin and lower lip within the distribution of the mental or inferior
alveolar nerves. Although commonly associated with local trauma, NCS can
indicate an underlying malignancy or can be the presenting symptom of
cancer recurrence. We describe the first pediatric patient with acute
myeloid leukemia (AML) who presents with NCS as a sign of AML recurrence
post allogeneic hematopoietic cell transplantation. We also review the
current literature on acute leukemia and NCS.