Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis(TEN) are
considered as delayed hypersensitivity reactions, and are among rare but
life-threatening medical emergency conditions. Survival is determined by
early diagnosis and appropriate treatment management. The most commonly
known reason is antibiotic use and anticonvulsants. However, with the
increased use of monoclonal antibodies today, reactions related to these
drugs are also reported. Here, we presented a case of Eculizumab-induced
Stevens-Johnson Syndrome, which had a monoclonal anti-C5 antibody.