loading page

First-generation Corona Virus Disease 2019 (COVID-19) patients with a Wuhan-traveling history are prone to more severe diseases
  • +10
  • Peiyan Zhang,
  • Jincheng Chen,
  • Guohui Xiao,
  • Peifen Chen,
  • Shuyang Liu,
  • Xiaoli Li,
  • Yinfeng Li,
  • Su Zhang,
  • Jing Bi,
  • Shiyan Feng,
  • Fuxiang Wang,
  • Guoliang Zhang,
  • Yingxia Liu
Peiyan Zhang
Author Profile
Jincheng Chen
Author Profile
Guohui Xiao
Author Profile
Peifen Chen
The Third People's Hospital of Shenzhen
Author Profile
Shuyang Liu
Author Profile
Yinfeng Li
Author Profile
Shiyan Feng
Author Profile
Fuxiang Wang
Author Profile
Guoliang Zhang
Author Profile
Yingxia Liu
Author Profile

Abstract

Wuhan has the highest number of deaths and mortality from COVID-19 in China to date, but the reason remains unknown. Here we compared patients with COVID-19 with a history of traveling in Wuhan with those who did not travel in Wuhan in the early stage of pandemic with respect to a series of clinical characteristics and laboratory parameters. We observed that patients who had traveled in Wuhan had an increased rate of severe disease and longer viral duration along with fewer CD4+ and CD8+ T cells, although there was no significant difference in viral load between the two groups.