loading page

Hypothermic circulatory arrest for aortic dissection with cryoglobulinemia
  • +12
  • Kazuhiro Yamazaki,
  • Kenji Minatoya,
  • Kazuhisa Sakamoto,
  • Koji Kitagori,
  • Masanori Okuda,
  • Hideo Kanemitsu,
  • Takahide Takeda,
  • Masahide Kawatou,
  • Jiro Sakai,
  • Motoyuki Kumagai,
  • Takashi Tsuji,
  • Kosaku Murakami,
  • Tsuneyasu Yoshida,
  • Yujiro Ide,
  • Tadashi Ikeda
Kazuhiro Yamazaki
Graduate School of Medicine, Kyoto University

Corresponding Author:[email protected]

Author Profile
Kenji Minatoya
Natl Cerebral
Author Profile
Kazuhisa Sakamoto
Graduate School of Medicine, Kyoto University
Author Profile
Koji Kitagori
Author Profile
Masanori Okuda
Author Profile
Hideo Kanemitsu
Graduate School of Medicine, Kyoto University
Author Profile
Takahide Takeda
Graduate School of Medicine, Kyoto University
Author Profile
Masahide Kawatou
Graduate School of Medicine, Kyoto University
Author Profile
Jiro Sakai
Graduate School of Medicine, Kyoto University
Author Profile
Motoyuki Kumagai
Kyoto University Graduate School of Medicine Department of Cardiovascular Surgery
Author Profile
Takashi Tsuji
Graduate School of Medicine, Kyoto University
Author Profile
Kosaku Murakami
Graduate of School of Medicine, Kyoto University
Author Profile
Tsuneyasu Yoshida
Graduate of School of Medicine, Kyoto University
Author Profile
Yujiro Ide
Graduate School of Medicine, Kyoto University
Author Profile
Tadashi Ikeda
Graduate School of Medicine, Kyoto University
Author Profile

Abstract

Cryoglobulinemia is a cold-reactive autoimmune disease. A 64-year-old man with active cryoglobulinemia presented Stanford type A acute aortic dissection. He had been treated with immunosuppressive drugs and plasma exchange (PE) at our hospital; subsequently, qualitative analysis of cryogobulin (CG) was negative. He underwent emergency ascending aorta replacement using cardiopulmonary bypass (CPB) under deep hypothermia circulatory arrest with selective cerebral perfusion. The total CPB time, aortic cross clamp time, and selective cerebral perfusion time were 255, 153, 56 minutes, respectively, and the minimal nasopharyngeal temperature was 17.3°C. Our patient had no significant perioperative complications. Hence, if PE is performed appropriately and CG is negative, patients with cryoglobulinemia who exhibit severe preoperative symptoms can safely undergo surgery with deep hypothermia.
12 Jun 2020Submitted to Journal of Cardiac Surgery
12 Jun 2020Submission Checks Completed
12 Jun 2020Assigned to Editor
12 Jun 2020Reviewer(s) Assigned
18 Jun 2020Review(s) Completed, Editorial Evaluation Pending
22 Jun 2020Editorial Decision: Revise Major
09 Jul 20201st Revision Received
10 Jul 2020Submission Checks Completed
10 Jul 2020Assigned to Editor
10 Jul 2020Reviewer(s) Assigned
20 Jul 2020Review(s) Completed, Editorial Evaluation Pending
20 Jul 2020Editorial Decision: Accept
Nov 2020Published in Journal of Cardiac Surgery volume 35 issue 11 on pages 3169-3172. 10.1111/jocs.14908