A Luminex based serological assay for detecting IgM and IgG antibody
response in SARS-CoV2 patients
Nucleic acid real-time PCR test has become the main diagnostic tool for
SARS‐CoV‐2 infection, and there are also drawbacks to these real-time
PCR test kits. Additionally, it has reported high false-negative rates.
A reliable and rapid test method is urgently required to briskly detect
antibody response in a large number of infected patients and ensure
prompt care for patients. Therefore, we report here a Luminex bead based
multiplexed immunoassay to serologically diagnose the SARS-CoV2
infection and detect IgM and IgG response in COVID-19 patients. The
technology can provide sensitive and specific detection using a low
amount of serum samples in high-throughput screening platforms.