loading page

Optically transparent electrodes to study living cells: a mini review
  • +2
  • Artem Kuzovlev,
  • Anatoly Evseev,
  • Irina Goroncharovskaya,
  • Aslan Shabanov,
  • Sergey Petrikov
Artem Kuzovlev
Federal research and clinical center of intensive care medicine and rehabilitology
Author Profile
Anatoly Evseev
N V Sklifosovsky Research Institute of Emergency Medicine
Author Profile
Irina Goroncharovskaya
N V Sklifosovsky Research Institute of Emergency Medicine
Author Profile
Aslan Shabanov
N V Sklifosovsky Research Institute of Emergency Medicine
Author Profile
Sergey Petrikov
N V Sklifosovsky Research Institute of Emergency Medicine
Author Profile

Abstract

The use of electrochemical methods to study living systems, including cells, has been of interest to researchers for a long time. Thus, controlling the polarization of the electrode contacting living cells, one can influence, for example, their proliferation or the synthesis of specific proteins. Moreover, the electrochemical approach formed the basis of the biocompatibility improvement of the materials contacting with body tissues that use in carbon hemosorbents and implants development. It became possible to reach a fundamentally new level in the study of cell activity with the introduction of optically transparent electrodes in this area. The use of such materials allowed approaching to the study of the influence of the electrode potential on adhesion activity and morphology of the different cell types (HeLa cells, endothelial cell, etc.) more detailed. There are a negligible number of publications in this area despite the obvious advantages of the usage of optically transparent electrodes to study living cells. This mini review is devoted to some aspects of the interaction of living cells with conductive materials and current advances in the use of optically transparent electrodes for the study of living cells, as well as the prospects for their use in cellular technologies.

Peer review status:Published

24 Jun 2020Submitted to Biotechnology and Bioengineering
25 Jun 2020Submission Checks Completed
25 Jun 2020Assigned to Editor
30 Jul 2020Reviewer(s) Assigned
06 Oct 2020Review(s) Completed, Editorial Evaluation Pending
06 Oct 2020Editorial Decision: Revise Major
26 Oct 20201st Revision Received
26 Oct 2020Assigned to Editor
26 Oct 2020Submission Checks Completed
11 Nov 2020Reviewer(s) Assigned
11 Feb 2021Review(s) Completed, Editorial Evaluation Pending
11 Feb 2021Editorial Decision: Revise Major
11 Mar 20212nd Revision Received
11 Mar 2021Assigned to Editor
11 Mar 2021Submission Checks Completed
30 Mar 2021Review(s) Completed, Editorial Evaluation Pending
30 Mar 2021Editorial Decision: Accept
23 Apr 2021Published in Biotechnology and Bioengineering. 10.1002/bit.27782