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Comparison of the International Association of the Diabetes and Pregnancy Study Group (IADPSG) criteria for diagnosis of gestational diabetes mellitus against a ‘one-stop’ diagnostic test: A Prospective Descriptive Cross Sectional study
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  • Gardie Role Malwattage Udara Jayawardena,
  • Krishnapillai Guruparan,
  • Dulika Sumathipala,
  • Udagama Don Ratnasiri,
  • Hemantha Senanayake
Gardie Role Malwattage Udara Jayawardena
Postgraduate Institute of Medicine University of Colombo
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Krishnapillai Guruparan
Postgraduate Institute of Medicine University of Colombo
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Dulika Sumathipala
University of Colombo Faculty of Medicine
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Udagama Don Ratnasiri
Desoysa Hospital for Women, Sri Lanka
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Hemantha Senanayake
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Abstract

Objective: The aim of this study was to investigate the utility of a single value non fasting glucose tolerance test as described by the Diabetes in Pregnancy Study Group of India (DIPSI) in detecting GDM Design: A Prospective Descriptive Cross Sectional study Setting: A Tertiary care maternity hospital in Sri Lanka. Sample: A sample of 165 pregnant women between 24-28 weeks of gestation was recruited Method: All women had the DIPSI and standard OGTT tests performed within a one week and results compared using standard non parametric tests. Main outcome measures:DIPSI and IADPSG criteria were compared using sensitivity, specificity and area under the ROC curve. Results: According to the IADPSG criteria 20% (33/165) had GDM, compared to 22.4% (37/165) detected by DIPSI. Sensitivity of DIPSI criteria was 64% while specificity was 88%. The area under receiver operator curve was 0.8. The mean satisfaction for DIPSI was of 8.9 ± 0.4, compared to 4.7 ± 1.3 for OGTT (p<0.001). Analysis of false positives showed that it was mainly due to elevated fasting values in the IADPSG criteria. Conclusion: Although DIPSI has a low sensitivity compared to the IADPSG criteria, area under the ROC curve is 0.80 indicating its utility for diagnosing GDM. It has additional advantages of allowing a diagnosis of GDM in a single visit and high acceptability among women. Funding: This study was self-funded Key words : Gestational Diabetes Mellitus, Diabetes in Pregnancy Study Group India, Oral Glucose Tolerence Test