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Systemic ALK-positive anaplastic large cell lymphoma with bilateral optic neurolymphomatosis resulting in permanent blindness
  • +6
  • Karan Seegobin,
  • Muhamad Alhaj Moustafa,
  • Deborah Fischer,
  • Katelyn Keller,
  • Jacquelyn Hastings,
  • Mohamed Kharfan Dabaja ,
  • Ernesto Ayala,
  • Han W. Tun,
  • Liuyan Jiang
Karan Seegobin
Mayo Clinic Hospital Jacksonville
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Muhamad Alhaj Moustafa
Mayo Clinic Hospital Jacksonville
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Deborah Fischer
Mayo Clinic Hospital Jacksonville
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Katelyn Keller
Mayo Clinic Hospital Jacksonville
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Jacquelyn Hastings
Mayo Clinic Hospital Jacksonville
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Mohamed Kharfan Dabaja
Mayo Clinic Hospital Jacksonville
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Ernesto Ayala
Mayo Clinic Hospital Jacksonville
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Han W. Tun
Mayo Clinic Hospital Jacksonville
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Liuyan Jiang
Mayo Clinic Hospital Jacksonville
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Abstract

A 26-year-old female developed bilateral blindness after a complete remission for ALK-positive ALCL. Initial workup showed neurolymphomatosis involving the bilateral optic nerves. She underwent hematopoietic cell transplantation and she remained in complete remission after 1 year; however her vision never improved. ALCL likely led to destruction of the optic pathway.

Peer review status:Published

01 Jul 2020Submitted to Clinical Case Reports
04 Jul 2020Assigned to Editor
04 Jul 2020Submission Checks Completed
15 Jul 2020Review(s) Completed, Editorial Evaluation Pending
20 Jul 2020Editorial Decision: Accept
14 Aug 2020Published in Clinical Case Reports. 10.1002/ccr3.3231