The Use of Ivabradine in a Patient with Idiopathic Ventricular
Arrhythmia Originating from the Left Ventricular Summit
Abstract
Idiopathic ventricular arrhythmias (VA) are common and treatment options
include anti-arrhythmic drugs (AAD) or catheter ablation. Patients
presenting with idiopathic VA which is originating from the left
ventricular summit (LVS) poses a particular challenge as the success for
catheter ablation is low and AAD’s may not be used long-term due to side
effects. Ivabradine is an inhibitor of funny current (If) in cardiac
pacemaker cells by blocking hyperpolarization-activated cyclic
nucleotide-gated (HCN) and recommended for the treatment of heart
failure with reduced ejection fraction and stable coronary artery
disease. Recently, several cases described patients with atrial and
junctional ectopic tachycardias who were successfully treated with
ivabradine. In the present case, we reported the use of ivabradine in
the treatment of idiopathic VA which was originated from the LVS and was
resistant to multiple AAD’s and catheter ablation.