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Pigs are not susceptible to SARS-CoV-2 infection but are a model for viral immunogenicity studies
  • +11
  • Júlia Vergara-Alert,
  • Jordi Rodon,
  • Jorge Carrillo,
  • Nigeer Te,
  • Nuria Izquierdo-Useros,
  • María Luisa Rodríguez de la Concepción,
  • Carlos Ávila-Nieto,
  • Víctor Guallar,
  • Alfonso Valencia,
  • Guillermo Cantero,
  • Julià Blanco,
  • Bonaventura Clotet,
  • Albert Bensaid,
  • Joaquim Segalés
Júlia Vergara-Alert
Institut de Recerca i Tecnologia Agroalimentaries (IRTA)
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Jordi Rodon
Institut de Recerca i Tecnologia Agroalimentaries (IRTA)
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Jorge Carrillo
IrsiCaixa Institut de Recerca de la Sida
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Nigeer Te
IRTA-CReSA
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Nuria Izquierdo-Useros
IrsiCaixa Institut de Recerca de la Sida
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María Luisa Rodríguez de la Concepción
IrsiCaixa Institut de Recerca de la Sida
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Carlos Ávila-Nieto
IrsiCaixa Institut de Recerca de la Sida
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Víctor Guallar
Barcelona Supercomputing Center
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Alfonso Valencia
Barcelona Supercomputing Center
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Guillermo Cantero
Institut de Recerca i Tecnologia Agroalimentaries (IRTA)
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Julià Blanco
IrsiCaixa Institut de Recerca de la Sida
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Bonaventura Clotet
IrsiCaixa Institut de Recerca de la Sida
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Albert Bensaid
Institut de Recerca i Tecnologia Agroalimentaries
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Joaquim Segalés
Universitat Autonoma de Barcelona
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Abstract

Conventional piglets were inoculated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) through different routes, including intranasal, endotracheal, intramuscular and intravenous ones. Although piglets were not susceptible to SARS-CoV-2 and lacked lesions or viral RNA in tissues/swabs, seroconversion was observed in pigs inoculated parenterally (intramuscularly or intravenously).

Peer review status:UNDER REVIEW

12 Jul 2020Submitted to Transboundary and Emerging Diseases
16 Jul 2020Submission Checks Completed
16 Jul 2020Assigned to Editor
17 Jul 2020Reviewer(s) Assigned
07 Aug 2020Review(s) Completed, Editorial Evaluation Pending
07 Aug 2020Editorial Decision: Revise Major
20 Aug 20201st Revision Received
20 Aug 2020Submission Checks Completed
20 Aug 2020Assigned to Editor
21 Aug 2020Reviewer(s) Assigned
05 Sep 2020Review(s) Completed, Editorial Evaluation Pending
06 Sep 2020Editorial Decision: Revise Minor
18 Sep 20202nd Revision Received
18 Sep 2020Submission Checks Completed
18 Sep 2020Assigned to Editor
19 Sep 2020Reviewer(s) Assigned