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Clinical impact of genomic characterization of 15 patients with acute megakaryoblastic leukemia related malignancies
  • +7
  • Emilie Lalonde,
  • Stefan Rentas,
  • Gerald Wertheim,
  • Lea Surrey,
  • Fumin Lin,
  • Xiaonan Zhao,
  • Amrom Obstfeld,
  • Richard Aplenc,
  • Minjie Luo,
  • Marilyn Li
Emilie Lalonde
The Children's Hospital of Philadelphia
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Stefan Rentas
The Children's Hospital of Philadelphia
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Gerald Wertheim
Children's Hospital of Philadelphia
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Lea Surrey
Children's Hospital of Philadelphia
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Fumin Lin
The Children's Hospital of Philadelphia
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Xiaonan Zhao
The Children's Hospital of Philadelphia
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Amrom Obstfeld
The Children's Hospital of Philadelphia
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Richard Aplenc
The Children’s Hospital of Philadelphia
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Minjie Luo
The Children's Hospital of Philadelphia
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Marilyn Li
The Children's Hospital of Philadelphia
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Abstract

Background: Acute megakaryoblastic leukemia (AMKL) is a rare subtype of acute myeloid leukemia but is ~500 times more likely to develop in children with Down syndrome (DS) thro