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Meta-analysis of the Efficacy of Magnetic Stimulation for Female Stress Urinary Incontinence
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  • Kai Sun,
  • Gang Wu,
  • Jipeng Wang,
  • Tianqi Wang,
  • Dongxu Zhang,
  • Yuanshan Cui,
  • Jitao Wu
Jipeng Wang
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Tianqi Wang
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Dongxu Zhang
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Yuanshan Cui
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Abstract

ABSTRACT Objective: Female stress urinary incontinence is one of the common diseases in menopausal women, which brings great inconvenience to life. We conducted a meta-analysis to evaluate the efficacy of magnetic stimulation (MS) in treating female stress urinary incontinence (SUI). Methods: The electronic databases (E-DB) MEDLINE, EMBASE and Cochrane Controlled Trial Registry system was used to retrieve the randomized controlled trials (RCTs) which recorded MS as a remedy to female SUI. Reference lists of related papers were carefully studied. Results: Six RCTs exploring the effect of MS in the treatment of female SUI were studied. We found that the MS group enjoyed a higher quality of life (QoL) (MD of 0.59, 95% CI of 0.23 to 0.95, P=0.001) and lower International Consultation on Incontinence Questionnaire (ICIQ) scores (MD of -3.93, 95% CI of -5.86 to -2.01, P<0.0001) and provided a higher objective cure rate (odds ratio [OR] of 8.49, 95% CI of 3.08 to 23.37) compared with the placebo group. Apart from this, MS treatment reduced the number of episodes of urinary incontinence (MD of -1.42, 95% CI of −2.24 to −0.59, P=0.0007) and urine loss on pad test (MD of −4.67 and 95% CI of −8.05 to −1.28, P=0.007). No significant treatment-related adverse reactions were reported. Conclusion: MS treatment showed a positive effect in the treatment of SUI and further trials are required to specify the best protocol to optimize the effect.