Improvement was needed in the standards of development for obstetrics
and gynecology core outcome sets
Abstract
Abstract Objectives This study aimed to investigate the characteristics
of obstetrics and gynecology (OG) core outcome sets (COSs) and assess
the report and design standards of OG COSs, and exploring how to improve
baseline standards for obstetrics and gynecology COSs development. Study
Design and Setting We conducted a comprehensive search of COMET database
on December 20, 2019. Two reviewers independently evaluated whether the
OG COS met the reporting requirement as stipulated in the Core Outcome
Set-STAndards for Reporting (COS-STAR) statement checklist and the
minimum design recommendations using the Core Outcome Set-STAndards for
Development (COS-STAD) checklist. Results Forty-four OG COSs focused on
26 topics. None met all the 25 standards of COS-STAR statement
representing 18 items considered essential for transparent and complete
reporting in all COS studies (range: 6.0-24.0, median: 14.0 ). The
compliance rates for the 16 standards of methods and result sections
ranged from 27.3% - 68.2%. Total COS-STAR compliance items of OG COSs
with the prior protocol was significantly higher than without prior
protocol (MD= 3.846, 95% CI: 0.835 - 6.858, P= 0.012). None of the OG
COSs met all the 12 criteria of COS-STAD minimum standards (range:
3.0-11.0, median: 5.0). The compliance rates for all three standards of
stakeholders involved and all four standards of the consensus process
were lower than 60%. Conclusion Methodological and reporting standards
of OG COSs should be further improved.