Abstract
Sickle beta + thalassemia (Sβ+) is considered to be a mild form of
sickle cell disease (SCD). However, some patients with mild disease can
present with osteonecrosis. Here, we present a three-year-old male who
presented with acute pain and baseline hemoglobin of 13 g/dL with
multifocal osteonecrosis of multiple areas in his vertebrae, pelvis and
femurs that improved with partial exchange transfusion and hydroxyurea.