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Recurrent cardiac intimal sarcoma misdiagnosed as a myxoma or malignant transformation of a cardiac myxoma?
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  • rodolphe Durieux,
  • Vincent Tchana-Sato,
  • Jean-Paul Lavigne,
  • marc Radermecker,
  • Marie Moonen,
  • Irène Scagnol,
  • Christine Gennigens,
  • Jean Olivier Defraigne
rodolphe Durieux
University Hospital of Liege Cardiovascular Surgery
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Vincent Tchana-Sato
University Hospital of Liège
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Jean-Paul Lavigne
University Hospital of Liege Cardiovascular Surgery
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marc Radermecker
University Hospital of Liège
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Marie Moonen
University Hospital of Liège
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Irène Scagnol
University Hospital of Liège
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Christine Gennigens
University Hospital of Liège
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Jean Olivier Defraigne
University Hospital of Liège
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Abstract

Cardiac intimal sarcoma are extremely rare and aggressive primary malignant cardiac tumors. Here, we reported the case of a young man initially operated for a tumor of the left atrium, causing a dynamic obstruction of the mitral valve and (mis-)diagnosed as a myxoma at the histopathological analysis. Patient presented a local recurrence at 3 months and was reoperated. Pathology revealed this time the presence of an intimal sarcoma. Patient received adjuvant chemotherapy. Despite a good local control, the one-year follow-up PET scan revealed the presence of a metastasis in the left adrenal gland that was surgically resected. This paper aims to highlight the risk of misdiagnosis in case of cardiac tumors, the hypothetical concept of malignant transformation of a cardiac myxoma, the aggressive course of the extremely rare cardiac intimal sarcoma and the therapeutic modalities available to treat this pathology.

Peer review status:IN REVISION

01 Aug 2020Submitted to Journal of Cardiac Surgery
07 Aug 2020Assigned to Editor
07 Aug 2020Submission Checks Completed
10 Aug 2020Reviewer(s) Assigned
20 Aug 2020Review(s) Completed, Editorial Evaluation Pending
25 Aug 2020Editorial Decision: Revise Major