A Dilemma for Women: Love of Multiple Children or Deterioration of
Diastolic Functions
Abstract
Echocardiography is the most widely used diagnostic tool for detecting
the cardiac functional changes. Pregnancy is a dynamic process that
affects cardiovascular system. Recent studies showed that increased
parity may cause irreversible changes in cardiovascular system. In this
study, we aimed to evaluate echocardiographic changes on women,
especially grand multiparous (up to 9 parities) and great grand
multiparous (more than 10 parities) women after all their pregnancies
finished. This is a cross-sectional study and contains 195 women
patients. Women with one delivery history was defined as primiparous
(PP), 2 to 5 deliveries were defined as multiparous (MP), 5 to 9
deliveries were defined as grand multiparous (GMP) and more than 9
deliveries were defined as great grand multiparous (GGMP). The mean age
was 50.6±16.3 and mean parity was 6.5±4.2. Spearman correlation analysis
showed that diastolic dysfunction has positive correlations with parity,
age, hypertension, and diabetes mellitus. ROC analysis showed that the
best cut-off value of the parity number for predicting left ventricular
diastolic dysfunction was 6.5, with 66.3% sensitivity and 66.7%
specificity. In present study, we showed that diastolic dysfunction
statistically increases as the number of pregnancies increases.
Additionally, cut of value of parity for diastolic dysfunction was 6.5
which is higher than other studies.