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Evaluation of Epidemiology, Clinical Features, Prognosis, Diagnosis and Treatment Outcomes of Patients with COVID-19
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  • Naser Garebaqi,
  • Saman Farshid,
  • Behdad Boroofeh ,
  • Rahim Nejadrahim,
  • Jalil Mousavi ,
  • Sina Dindarian,
  • Sedra Mohamadi,
  • Rohollah Valizadeh
Naser Garebaqi
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Saman Farshid
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Behdad Boroofeh
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Rahim Nejadrahim
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Jalil Mousavi
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Sina Dindarian
Urmia University of Medical Sciences
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Sedra Mohamadi
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Rohollah Valizadeh
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Abstract

Background: COVID-19 is considered a widespread concern in global public health. Diagnoses of COVID-19 in some cases are necessary due to severe prognosis. In this study, clinical and demographic characteristics of patients with COVID-19 were studied in Taleghani Hospital, Urmia, Iran. Methods: This descriptive-analytical cross-sectional (retrospective) study carried out on 215 patients with COVID-19 during March and April 2020.. Approved COVID-19 case was considered as a person with a positive respiratory sample performed by at least one of two RT-PCR methods or genetic sequencing. Results: The mean age of patients was 50.93±17.92 years. The mean hospital stay, the temperature at admission, and onset of symptoms were 4.91±3.68 days, 37.40±0.96 0C, and 5.88±4.80 days, respectively. Shortness of breath and cough were found in 62.8 % and 49.3 % of patients. Regarding lung involvement, 33 patients (33%) were normal, most of the patients (n=71) had 5-25% involvement in their lung and a minority of patients (n=13) had a severe condition of 50-75% lung involvement. .Spo2 can increase the risk of death by 16% with each unit reduction. Kidney involvement increases the chance of mortality by 1.386 times (95% CI: 11.010-2.704). Hemoglobin was also significantly marginal, with a 35% risk of death per unit reduction in blood hemoglobin, which is a very important finding in this study. The odds ratio of spo2 and hemoglobin for mortality due to COVID-19 was 1.16 (95% CI: 1.073-1.262) and 1.350 (95% CI: 0.989-1.842), respectively. Conclusion: COVID-19, like other viral diseases, can involve different organs of the body with different severity. In the meantime, smoking was not a risk factor for the virus or associated with severe manifestations of the disease. Patients with high creatinine and CPK, pulmonary involvement above 25%, and hypoxemia had a higher mortality

Peer review status:UNDER REVIEW

14 Aug 2020Submitted to International Journal of Clinical Practice
19 Aug 2020Assigned to Editor
19 Aug 2020Submission Checks Completed
20 Sep 2020Reviewer(s) Assigned
21 Sep 2020Review(s) Completed, Editorial Evaluation Pending