Introduction Idiopathic hyper eosinophilic syndrome (HES) is a rare
disease characterized by sustained increase in eosinophilia. Lesions can
affect various organs and systems. The global prevalence rate is
unknown, and the prognosis is poor. At present, most of the literature
reports are based on cases. Heart involvement may be present in 50% to
60% of patients, this is called Loffler endocarditis. Loffler
endocarditis is a serious complication of hyper eosinophilia syndrome,
which is characterized by a special type of fibrotic endocarditis.
Loffler endocarditis is an inflammatory cardiac condition characterized
by eosinophilic infiltration in the heart. Methods In this article we
report an 8-year-old girl who was diagnosed as having Loffler
endocarditis in thrombotic phase and treated by surgery successfully.
Results Our patient had a good prognosis during the follow up of half
year. She had no symptoms of heart failure and echocardiography findings
were normal. Discussion The cardiac damage occurs in three stage
processes: the necrotic, thrombotic, and fibrotic stages. This unusual
but sometimes life-threatening disease is often detected in the late
phase, resulting in no curative strategy available to reverse the
disease process. The overall prognosis of patients with Loffler
endocarditis is very poor. Current treatments include anticoagulation
and anti-eosinophils therapy，surgery only used in selected cases.
Surgical treatment of HES in adolescents is very rare. The present case
illustrates that with well controlled peripheral eosinophilia, proper
surgical treatment in selected patients can improve their prognosis in
the near future but long-term follow up is necessary.