Impacting the COVID-19 Pandemic by Inducing Temporary Non-Specific
AbstractFollowing respiratory viral infections, there is a brief window in which
a host has less susceptibility to other respiratory viruses. This is
essential, as it may take up to 1 year to develop a vaccine. Most people
get SARS-CoV-2 from their infected relatives at home, particularly
during the first two weeks after exposure. Self-quarantine does not
necessarily reduce the level of exposure for the relatives interacting
with infected patients. The new infection may happen at least 10-14 days
after the first infection. We propose to induce other viral respiratory
infections such as non-fatal, mild, and self-limited Rhinoviruses or
Coronavirus, which cause the common cold, prior to exposure to COVID-19.
This would be beneficial for surrounding community members of infected
individuals. In conclusion, theoretically we may protect immediate
relatives of an infected person for at least two weeks, during active
screening, by inducing temporary-immunity through the administration of
non-fatal respiratory viruses.