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Upper Gastrointestinal Ischemia as a Rare Complication of Paroxysmal Nocturnal Hemoglobinuria
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  • Masayuki Ueno,
  • Yuichi Shimodate,
  • Kazuya Okada,
  • Ryosuke Takaya,
  • Hiroshi Yamamoto,
  • Motowo Mizuno
Masayuki Ueno
Kurashiki Central Hospital
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Yuichi Shimodate
Kurashiki Central Hospital
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Kazuya Okada
Kurashiki Central Hospital
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Ryosuke Takaya
Kurashiki Central Hospital
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Hiroshi Yamamoto
Kurashiki Central Hospital
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Motowo Mizuno
Kurashiki Central Hospital
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Abstract

Here, we report a case of PNH with gastroduodenal lesions likely caused by transient mucosal ischemia due to thrombosis. When patients with PNH present with abdominal symptoms, thrombosis-induced gastrointestinal injury should be considered. Recognition of gastric patchy redness on esophagogastroduodenoscopy may help make the diagnosis of this potentially serious complication.

Peer review status:UNDER REVIEW

13 Aug 2020Submitted to Clinical Case Reports
18 Aug 2020Assigned to Editor
18 Aug 2020Submission Checks Completed
07 Sep 2020Reviewer(s) Assigned