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Efficacy and safety of low-dose imatinib in an elderly patient with mixed phenotype acute leukemia with t(9;22)(q34;q11.2);BCR-ABL1
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  • Yusuke Okayama,
  • Teruhito Takakuwa,
  • Ippei Otomaru,
  • mirei horiuchi,
  • Akiko Miura,
  • Taku Araki,
  • Yotaro Fujitani,
  • Ryosuke Yamamura
Yusuke Okayama
Osaka City University Graduate School of Medicine Department of Hematology
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Teruhito Takakuwa
Osaka City University Graduate School of Medicine School of Medicine
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Ippei Otomaru
Saiseikai Nakatsu Hospital
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mirei horiuchi
Saiseikai Nakatsu Hospital
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Akiko Miura
Saiseikai Nakatsu Hospital
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Taku Araki
Saiseikai Nakatsu Hospital
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Yotaro Fujitani
Saiseikai Nakatsu Hospital
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Ryosuke Yamamura
Saiseikai Nakatsu Hospital
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Abstract

Optimal treatment for Philadelphia chromosome-positive mixed phenotype acute leukemia (Ph+ MPAL), particularly in elderly patients with comorbidities, has not been established. We present the elderly Ph+ MPAL case who discontinued initial treatment with dasatinib and whose disease was successfully controlled by low-dose imatinib with monitoring of drug concentrations in blood.

Peer review status:POSTED

27 Aug 2020Submitted to Clinical Case Reports
01 Sep 2020Assigned to Editor
01 Sep 2020Submission Checks Completed