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Hypertensive cerebral hemorrhage with undetectable plasma VEGF after intravitreal injection of aflibercept for diabetic macular edema
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  • Miwako Yoshimoto,
  • Nobuhiko Takeda,
  • Takayuki Yoshimoto,
  • Shun Matsumoto
Miwako Yoshimoto
Tokyo Teishin Hospital
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Nobuhiko Takeda
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Takayuki Yoshimoto
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Shun Matsumoto
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Anti-vascular endothelial growth factor (VEGF) therapy is widely used to maintain visual functioning in macular diseases including diabetic macular edema (DME). We report a case of a hypertensive cerebral hemorrhage even after intravitreal injections of aflibercept for DME in which the patient’s plasma VEGF levels were below the detection limit.