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AN EARLY PREDICTION MODEL FOR FUNCTIONAL MYOCARDIAL RECOVERY IN ST ELEVATION MYOCARDIAL INFARCTION
  • Alper Karakus,
  • Berat UGUZ
Alper Karakus
Besni State Hospital
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Berat UGUZ
Bursa City Hospital
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Abstract

Objective. Discrimination of the time course of functional recovery in early period following STEMI has prognostic importance. This study aims to establish the ability of this combined systolic-diastolic index (E/(Ea x Sa), for differentiating recoverable myocardium or persistent non-viability in subjects with STEMI. Methods. 77 patients with first acute STEMI were enrolled to the study. To assess the association between E/(Ea x Sa) index and myocardial recovery, two categories(Transient stunning and persistent non-viability) were defined on basis of improvement of EF. Results. 71.4% of patients had improvement of LV EF and 28.6% had no recovery of systolic function (48.78±6.1 vs. 39.31±8.1, p=0.01).The E/(Ea × Sa) index (Predischarge and control values) were significantly higher in the “non-viability” than in stunning group (Respectively 1.61±0.64 vs. 1.25±0.43 , p=0.01 and 1.33±0.25 vs. 1.14±0.21, p = 0.01). The decrease ratio of index in early period (Within 5 ± 1 days) higher in the stunning group (26%) compared to non-viability group (15%) (p = 0.033). E / (Ea × Sa) index was found to be a significant predictor of myocardial recovery in multivariable logistic regression (Beta = -5.70 ± 1.72, p = 0.001). Roc curve shows that the cutoff value of E/(Ea x Sa) index is 1.29 with sensitivity (73%) and specificity (61%). Conclusion. Our findings suggest that E/(Ea x Sa) index is a strong predictor of functional recovery; the odds of recovery decrease as E/(Ea x Sa) index value increase.

Peer review status:UNDER REVIEW

14 Sep 2020Submitted to Echocardiography
15 Sep 2020Assigned to Editor
15 Sep 2020Submission Checks Completed
16 Sep 2020Reviewer(s) Assigned