What is the filling defects of pulmonary trunk: a rare case of pulmonary
leiomyosarcoma
Abstract
Background: Leiomyosarcoma occurs commonly in the abdomen,
retroperitoneum, large blood vessels, and uterus[1]. Cardiac
leiomyosarcoma is a rare and highly aggressive sarcoma. Methods and
Results: Here, we report the case of a 63-year-old male with pulmonary
artery leiomyosarcoma. Transthoracic echocardiography showed a large
4.4×2.3 cm hypoechoic mass in right ventricular outflow tract and
pulmonary artery. Pulmonary computed tomography angiography showed a
filling defect in similar location. Surgery was performed due to tend to
occlusion. A yellow mass adhered to ventricular septum and pulmonary
artery wall was detected and compressed pulmonary valve. By
immunohistochemistry, the tumor cells stained positive for Desmin and
smooth muscle actin, and stained negative for S-100, CD34, myogenin, or
myoglobin, KI67(+)80%, supported leiomyosarcoma. Conclusion: The
patient had recovered from surgery and had been on following-up.