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Allergen Immunotherapy in Atopic Dermatitis: light and shadow in children.
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  • lucia Caminiti,
  • ILENIA PANASITI,
  • Massimo Landi,
  • Maria De Filippo,
  • Roberta Olcese,
  • Giorgio Ciprandi,
  • Vernich Mario ,
  • Carelli Francesco,
  • Martina Votto,
  • Salvatore Barberi
lucia Caminiti
University of Messina
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ILENIA PANASITI
Universita degli Studi di Messina
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Massimo Landi
National Pediatric Healthcare System
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Maria De Filippo
University Hospital of Montpellier, Arnaud de Villeneuve
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Roberta Olcese
Istituto Giannina Gaslini
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Giorgio Ciprandi
2 Allergy and Respiratory Diseases Clinic
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Vernich Mario
ASST-Rhodense, RHO Milan
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Carelli Francesco
Azienza Ospedaliera Universitaria, Policlinic Giovanni XXIII
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Martina Votto
Fondazione IRCCS Policlinico San Matteo
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Salvatore Barberi
Ospedale San Paolo, Milano
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Abstract

Atopic dermatitis (AD) is a chronic remitting-relapsing inflammatory skin disorder. Due to the multifactorial pathogenesis, there are numerous therapeutic management approaches, mainly based on symptomatic treatments. In recent years Allergen Immunotherapy (AIT) has been progressively advanced as targeted disease-modifying treatment of allergic disease. The most recent guideline from the American Academy of Dermatology concludes that data available do not support its use in AD. The Joint Task Force and The European Academy of Dermatology suggest that clinicians can consider AIT treatment in selected patients characterized by aeroallergen sensitization, prevalently HDM, severe AD, clinical exacerbation after exposure to the causative allergen. Nevertheless, its role in AD is still under debate, especially in children.

Peer review status:Published

07 Aug 2020Submitted to Pediatric Allergy and Immunology
23 Sep 2020Review(s) Completed, Editorial Evaluation Pending
23 Sep 2020Editorial Decision: Revise Minor
24 Sep 20201st Revision Received
26 Sep 2020Review(s) Completed, Editorial Evaluation Pending
28 Sep 2020Editorial Decision: Revise Major
30 Sep 20202nd Revision Received
30 Sep 2020Review(s) Completed, Editorial Evaluation Pending
30 Sep 2020Editorial Decision: Accept
Nov 2020Published in Pediatric Allergy and Immunology volume 31 issue S26 on pages 46-48. 10.1111/pai.13390