Myeloid sarcoma refers to the extramedullary deposition of myeloblasts characteristically seen in AML-FAB types M2, M4 and M5. Commonest sites include skin, orbit and lymph nodes. Myeloid sarcoma in heart is an extremely rare occurrence and usually leads to delayed diagnosis owing to consideration of other differentials and technical difficulties in obtaining tissue for biopsy. Overall survival rate as per available literature is 20-30%. Non-invasive mode of diagnosis, timely initiation of chemotherapy and meticulous supportive care are the keys to successful outcome.