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Simultaneous intraocular and cutaneous extranodal NK/T cell lymphoma refractory to multiple therapies including pembrolizumab
  • +2
  • Peter Mallal,
  • Benhur Amanuel,
  • Rohen White,
  • Chris Kennedy,
  • Chan Cheah
Peter Mallal
Sir Charles Gairdner Hospital
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Benhur Amanuel
Sir Charles Gairdner Hospital
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Rohen White
Sir Charles Gairdner Hospital
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Chris Kennedy
Saint John of God Hospital Subiaco
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Chan Cheah
Sir Charles Gairdner Hospital
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Abstract

An 80 year old woman underwent vitrectomy for recurrent uveitis, demonstrating lymphocytic vitreous fluid. Less than a month later skin biopsy confirmed the diagnosis of extranodal NK/T cell lymphoma. Chemotherapy with SMILE (steroid - dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide) was poorly tolerated despite reduced doses, while pembrolizumab was ineffective.

Peer review status:Published

26 Sep 2020Submitted to Clinical Case Reports
30 Sep 2020Submission Checks Completed
30 Sep 2020Assigned to Editor
09 Oct 2020Reviewer(s) Assigned
13 Jan 2021Review(s) Completed, Editorial Evaluation Pending
13 Jan 2021Editorial Decision: Revise Minor
22 Mar 20211st Revision Received
24 Mar 2021Submission Checks Completed
24 Mar 2021Assigned to Editor
24 Mar 2021Review(s) Completed, Editorial Evaluation Pending
01 Apr 2021Reviewer(s) Assigned
02 Apr 2021Editorial Decision: Accept
May 2021Published in Clinical Case Reports volume 9 issue 5. 10.1002/ccr3.4194