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Pulmonary Embolism complicated Acute Chest Syndrome due to SARS-CoV-2 in adolescents with Sickle Cell Disease
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  • Milena Demey,
  • Laurence Dedeken,
  • Catherine Heijmans,
  • Pierre Smeesters,
  • Anne Tilmanne,
  • Marco Preziosi,
  • Alina Ferster
Milena Demey
Hôpital Universitaire des Enfants Reine Fabiola
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Laurence Dedeken
Hôpital Universitaire des Enfants Reine Fabiola
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Catherine Heijmans
Hôpital Universitaire des Enfants Reine Fabiola
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Pierre Smeesters
Hôpital Universitaire des Enfants Reine Fabiola
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Anne Tilmanne
Hôpital Universitaire des Enfants Reine Fabiola
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Marco Preziosi
Hôpital Universitaire des Enfants Reine Fabiola
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Alina Ferster
Hôpital Universitaire des Enfants Reine Fabiola
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Abstract

SARS-CoV-2 causes a hypercoagulable state that predisposes patients to thromboembolic events. We report two adolescents with Sickle Cell Disease (SCD) who developed pulmonary embolism (PE) during acute chest syndrome (ACS) episode associated with a possible SARS-CoV-2 infection. Both SCD and SARS-CoV-2 infection predisposes to thromboembolic disease. Thromboprophylaxis with LMWH should be considered in adolescent with ACS, related or not to COVID-19 disease.