Pulmonary Embolism complicated Acute Chest Syndrome due to SARS-CoV-2 in
adolescents with Sickle Cell Disease
SARS-CoV-2 causes a hypercoagulable state that predisposes patients to
thromboembolic events. We report two adolescents with Sickle Cell
Disease (SCD) who developed pulmonary embolism (PE) during acute chest
syndrome (ACS) episode associated with a possible SARS-CoV-2 infection.
Both SCD and SARS-CoV-2 infection predisposes to thromboembolic disease.
Thromboprophylaxis with LMWH should be considered in adolescent with
ACS, related or not to COVID-19 disease.