H5N1 hybrid of avian and human influenza viruses in farmed minks with
pandemic potential
- Jiahui Liu,
- Jiming Chen,
- Haiyan Yang,
- Jianlin Wang,
- Qingxia Ma,
- Xuwei Qin,
- Chuanmei Zhang
Abstract
We isolated avian, swine, human influenza viruses, and one hybrid
influenza virus from minks in China. The H5N1 hybrid virus had pandemic
potential because its seven genomic segments were from H1N1 human
influenza virus and its HA gene was from H5N6 highly pathogenic avian
influenza virus carrying multiple mammalian-adaptive mutations.
