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Study on perinatal related factors of maternity and newborn in parturients with intrapartum fever: a retrospective study
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  • Yuru Fan,
  • Chong Fan,
  • Pengyuan Mao,
  • Can Rui,
  • Xinyan Wang,
  • Wenwen Hou,
  • Ting Luan,
  • Zhiyong Dong,
  • Ping Li,
  • Shanwu Feng,
  • Xin Zeng
Yuru Fan
Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital

Corresponding Author:[email protected]

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Chong Fan
Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital
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Pengyuan Mao
Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital
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Can Rui
Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital
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Xinyan Wang
Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital
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Wenwen Hou
Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital
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Ting Luan
Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital
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Zhiyong Dong
Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital
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Ping Li
Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital
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Shanwu Feng
Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital
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Xin Zeng
Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital
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Abstract

Objective To investigate the impact of intrapartum fever on maternity and fetus. Design Retrospective cohort study. Setting Women’s Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China Population We studied intrapartum fever, as well as non-fever parturients, between January 1, 2018 and December 31, 2018. Methods We collected pregnancy outcomes of intrapartum fever and non-fever mother and neonatal data. Main outcomes and measures The obstetrics outcomes, complete blood cell count (CBC) and thereby converted neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and monocyte to lymphocyte ratio (MLR), as well as vaginal secretion were observed in women with and without intrapartum fever. Results Prepartum white blood cell (WBC), red blood cell (RBC), and hemoglobin (Hb) were all higher in febrile group, and WBC still higher but RBC and Hb lower after birth. Postpartum NLR and MLR were all higher in fever group but not preferred overtly difference before delivery. Additionally, the comparison of WBC, RBC, Hb, platelets (PLT), neutrophils, and monocytes in prepartum and postpartum all showed significant difference. Conclusions The differences of the prepartum WBC, RBC, Hb, and monocytes existed in the intrapartum fever and afebrile groups. Besides, the parturition could bring about the change of the value of CBC and intrapartum fever might aggravate or alleviate this change. Additionally, the intrapartum fever might not be caused mainly by infection and the difference between bacteria and fungus could reflect in the CBC. Keywords: Intrapartum fever, perinatal period, vaginal discharge examination