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In COVID-19 pneumonia, high-sensitive troponin I independently related with tricuspid regurgitation pressure gradient
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  • Akkan Avci,
  • Hilmi Erdem Sumbul,
  • Yahya Kemal Icen,
  • Abdullah Orhan Demirtas,
  • Huseyin Ali Ozturk,
  • Arzu Pinar,
  • Edip Bayrak,
  • Mehmet Uzucek,
  • Begum Seyda Avci,
  • Onder Yesiloglu,
  • Salim Satar,
  • Hayri Cinar,
  • Hasan Koca,
  • Burcak Cakir Pekoz,
  • Tuba Turunc,
  • Ilker Unal,
  • Murat Erdogan,
  • Mevlut Koc
Akkan Avci
Health Science University, Adana City Research and Training Hospital
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Hilmi Erdem Sumbul
Health Science University, Adana City Research and Training Hospital
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Yahya Kemal Icen
Health Science University, Adana City Research and Training Hospital
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Abdullah Orhan Demirtas
Health Science University, Adana City Research and Training Hospital
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Huseyin Ali Ozturk
Health Science University, Adana City Research and Training Hospital
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Arzu Pinar
Health Science University, Adana City Research and Training Hospital
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Edip Bayrak
Health Science University, Adana City Research and Training Hospital
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Mehmet Uzucek
Health Science University, Adana City Research and Training Hospital
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Begum Seyda Avci
Health Science University, Adana City Research and Training Hospital
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Onder Yesiloglu
Health Science University, Adana City Research and Training Hospital
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Salim Satar
Health Science University, Adana City Research and Training Hospital
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Hayri Cinar
Health Science University, Adana City Research and Training Hospital
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Hasan Koca
Health Science University, Adana City Research and Training Hospital
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Burcak Cakir Pekoz
Health Science University, Adana City Research and Training Hospital
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Tuba Turunc
Health Science University, Adana City Research and Training Hospital
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Ilker Unal
Cukurova University Faculty of Medicine
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Murat Erdogan
Health Science University, Adana City Research and Training Hospital
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Mevlut Koc
Health Science University, Adana City Research and Training Hospital
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Abstract

Background: We aimed to determine the clinical, laboratory and echocardiographic parameters associated with an increased high-sensitivity cTnI (hs-cTnI) levels in COVID-19 pneumonia who admitted to the emergency department. Methods: This cross-sectional study included 70 COVID-19 patients with and without pneumonia. In addition to medical history, physical examination and laboratory tests, echocardiography and lung computed tomography was performed. The hs-cTnI value of the patients’ ≥14ng/L for men and ≥18ng/L for women was considered as an increased hs-cTnI. The patients were compared in two groups, with and without pneumonia. Results: Tricuspid regurgitation pressure gradient (TRPG) were higher in patients with COVID-19 pneumonia (p<0.05). Tricuspid annular plane systolic excursion (TAPSE) were lower in patients with COVID-19 pneumonia (p<0.05). In regression analysis; HR, NT-proBNP and TRPG was found to be related to hs-cTnI (p<0.01). Discussion: The most important determinants of increased hs-cTnI level in these patients are; increased NT-proBNP and TRPG. Therefore, it is necessary to follow-up the RV functions and TRPG by echocardiography in patients with increased hs-cTnI and COVID-19 pneumonia.