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Case Series of Hemolysis in Neonate Born to Mothers with History of SARS-CoV-2 Infection During Pregnancy
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  • Elena Itriago,
  • Krithika Lingappan,
  • Jun Teruya,
  • Daniela Dinu
Elena Itriago
Baylor College of Medicine
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Krithika Lingappan
Baylor College of Medicine
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Jun Teruya
Baylor College of Medicine
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Daniela Dinu
Baylor College of Medicine
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Abstract

Hemolytic anemia has been associated with SARS-CoV-2 infection in adult and pediatric patients, we report a case series of preterm newborns with hemolytic anemia whose mothers had a history of SARS-CoV-2 infection. In two of the cases maternal infection occurred early in pregnancy and the newborns had a reactive SARS-CoV-2 antibody test. Hemolysis and coagulopathy improved with the use of washed blood products and prothrombin complex concentrate. Our cases highlight the need for increased awareness of a possible association between hemolysis and exposure to SARS-CoV-2 infection during intrauterine life.