Objective to evaluate the efficiency and safety of a novel technique to keep benefits of laparoscopic management in women with large ovarian benign cysts without affection of the ovarian reserve Design: An interventional study Setting: Kasr Alainy medical school, Cairo university hospital Population: 112 women with large benign ovarian cyst candidate for ovarian cystectomy. Methods: The technique started with laparoscopy followed by guided cyst aspiration followed by exteriorization of the ovary through minilaprotomy and completion of cystectomy through microsurgical technique. Main Outcome Measures: The primary outcome was ipsilateral recurrence of the cyst. Other outcomes included ovarian reserve assessment and postoperative pain. Results: The number of women with recurrence in the ipsilateral ovary after 12, 18 and 24 months were 5 (4.5%),16 (14.3%),20 (17.85%) respectively. Assessment of ovarian reserve revealed a significant decrease in the level of serum AMH (2.82±0.44 vs. 2.50±0.42) and a significant increase in AFC (3.5±1.7 vs. 4.9±1.3) after our novel technique in the surgical treatment of ovarian cysts (P-value <0.001). The operative time was 50±7 and 62±7 minutes in unilateral and bilateral cysts respectively. Conclusions: Laparoscopic guided minilaparotomy is a safe and effective technique for the management of large benign ovarian cysts with minimal recurrence rate, ovarian reserve affection, and adhesions.