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How we approach the diagnosis and management of complex lymphatic anomalies
  • Kiersten Ricci,
  • Ionela Iacobas
Kiersten Ricci
Cincinnati Children's Hospital Medical Center
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Ionela Iacobas
Baylor College of Medicine
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Abstract

Complex lymphatic anomalies are congenital diseases of the lymphatic circulation system that are associated with significant morbidity and early mortality. While guidelines for the comprehensive evaluation of the complex lymphatic anomalies were recently published, the diagnostic approach and medical management are not standardized. The current manuscript presents the clinical features of 4 complex lymphatic anomalies: Gorham-Stout disease, generalized lymphatic anomaly, kaposiform lymphangiomatosis, and central collecting lymphatic anomaly. We also offer three cases from the authors’ practice and our views on diagnostic testing and disease management including supportive care, medical therapies and other interventions.

Peer review status:ACCEPTED

21 Nov 2020Submission Checks Completed
21 Nov 2020Assigned to Editor
21 Nov 2020Submitted to Pediatric Blood & Cancer
26 Nov 2020Reviewer(s) Assigned
20 Dec 2020Review(s) Completed, Editorial Evaluation Pending
10 Jan 2021Editorial Decision: Revise Minor
29 Jan 2021Submission Checks Completed
29 Jan 2021Assigned to Editor
29 Jan 20211st Revision Received
07 Feb 2021Reviewer(s) Assigned
07 Feb 2021Review(s) Completed, Editorial Evaluation Pending
13 Feb 2021Editorial Decision: Accept