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Clinical management of vesicoureteral reflux with respect to EAU Guidelines: A multicenter study
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  • Eda Tokat,
  • Serhat Gurocak,
  • Seçil Özkan,
  • Hasan Serkan Dogan,
  • Burak Citamak,
  • Nihat Satar,
  • Volkan Izol,
  • Mutlu Deger,
  • Şaban Sarıkaya,
  • Yakup Bostancı,
  • Murat Gülşen,
  • Bülent Önal,
  • Elif Altınay Kırlı,
  • Berk Burgu,
  • Tarkan Soygür,
  • Koray Ağras,
  • Bilge Karabulut,
  • Cem Akbal,
  • Çağrı Akın Şekerci,
  • Deniz Demirci,
  • Numan Baydilli,
  • Serdar Tekgul,
  • Mustafa Özgür Tan
Eda Tokat
Sağlık Bakanlığı Ankara Eğitim ve Araştırma Hastanesi
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Serhat Gurocak
Gazi University Faculty of Medicine
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Seçil Özkan
Gazi University Faculty of Medicine
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Hasan Serkan Dogan
Hacettepe University Faculty of Medicine
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Burak Citamak
Hacettepe University
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Nihat Satar
Çukurova Üniversitesi Tıp Fakültesi
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Volkan Izol
Cukurova University Faculty of Medicine
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Mutlu Deger
Cukurova University Faculty of Medicine
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Şaban Sarıkaya
Ondokuz Mayis University Faculty of Medicine
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Yakup Bostancı
Ondokuz Mayis Universitesi Tip Fakultesi
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Murat Gülşen
Ondokuz Mayis University Faculty of Medicine
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Bülent Önal
İstanbul Üniversitesi-Cerrahpaşa Cerrahpaşa Tıp Fakültesi
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Elif Altınay Kırlı
İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi
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Berk Burgu
Ankara University Faculty of Medicine
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Tarkan Soygür
Ankara University Faculty of Medicine
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Koray Ağras
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Bilge Karabulut
Ankara Child Health Diseases Hematology Oncology Training And Research Hospital
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Cem Akbal
Acibadem Universitesi Tip Fakultesi
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Çağrı Akın Şekerci
Marmara University School of Medicine
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Deniz Demirci
Erciyes Universitesi Tip Fakultesi
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Numan Baydilli
Erciyes University
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Serdar Tekgul
Hacettepe University
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Mustafa Özgür Tan
Gazi University Faculty of Medicine
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Abstract

Purpose: We designed a multicenter, retrospective study to investigate the current trends in initial management of reflux with respect to EAU guidelines in Urology clinics of our country. Materials and Methods: The study group consisted of 1988 renal units (RU) of 1345 patients treated surgically due to VUR between years 2003-2017 in 9 different institutions. Patients were divided into 2 groups according to time of initial treatment and also grouped according to risk factors by “EAU guidelines on VUR”. Results: 1426 RUs were treated initially conservatively and 562 RUs were initially treated with surgery. In initially surgically treated group, success rates of surgery decreased significantly in low and moderate risk groups after 2013 (p=0.046, p=0.0001, respectively), while success rates were not significantly different in high risk group (p=0.46). While 26.6% of patients in low risk group were initially surgically treated before 2013, this rate has increased to 34.6% after 2013, but the difference was not statistically significant (p=0.096). However, performing surgery as the initial treatment approach increased significantly in both moderate and high risk groups (p=0.000 and p=0.0001, respectively) after 2013. Overall success rates of endoscopic and UNC operations were 65% and 92.9% before 2013, 60% and 78.5% after 2013, respectively. Thus the overall success rate for surgery was 72.6%. There was significant difference between success rates of UNC operations before and after 2013(p=0.000), while the difference was not significant in the STING group (p=0.076). Conclusion: Current trends in management of reflux in our country do not yet follow the EAU guidelines on VUR in low and moderate risk groups.

Peer review status:ACCEPTED

09 Dec 2020Submitted to International Journal of Clinical Practice
10 Dec 2020Submission Checks Completed
10 Dec 2020Assigned to Editor
11 Dec 2020Reviewer(s) Assigned
21 Apr 2021Review(s) Completed, Editorial Evaluation Pending
03 May 20211st Revision Received
04 May 2021Submission Checks Completed
04 May 2021Assigned to Editor
04 May 2021Review(s) Completed, Editorial Evaluation Pending
04 May 2021Editorial Decision: Accept