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High-flow nasal cannula for respiratory evaluation of surfactant protein C dysfunction
  • +3
  • Masao Nogami,
  • Soichiro Wada,
  • Shuji Sai,
  • Taiji Nakashima,
  • Tetuo Onda,
  • K. Cho
Masao Nogami
Teine Keijinkai Hospital
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Soichiro Wada
Teine Keijinkai Hospital
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Shuji Sai
Teine Keijinkai Hospital
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Taiji Nakashima
Japan Community Health Care Organisation Hokkaido Hospital
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Tetuo Onda
Hokkaido University Hospital
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K. Cho
Hokkaido University Hospital
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Abstract

Surfactant protein C gene (SFTPC) variations may cause hereditary interstitial lung disease (HILD), a disease with variable prognosis. The evaluation of treatment responsiveness of HILD with SFTPC variation remains unclear. We present the case of a child with HILD whose respiratory condition was appropriately evaluated using a high-flow nasal cannula (HFNC). A 12-month-old boy with SFTPC variation developed progressive respiratory failure. Although he was once considered a candidate for lung transplantation, his respiratory condition was improved by hydroxychloroquine treatment, which prevented further therapy. Compared to a conventional nasal cannula, which could not deliver a stable oxygen concentration, HFNC allowed us to evaluate the improvement of oxygenation more accurately.