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Does the anthropometric profile influence infection morbidity after coronary artery bypass grafting?
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  • Fernando Atik,
  • Helio Pegado,
  • Larissa de Brito,
  • Murilo Macedo,
  • Edilson França Junior,
  • Adhamys Dias,
  • Vitor Barzilai,
  • Renato Chaves,
  • Rodrigo Biondi,
  • Guilherme Monte,
  • Claudio da Cunha
Fernando Atik
Instituto de Cardiologia do Distrito Federal

Corresponding Author:[email protected]

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Helio Pegado
Instituto de Cardiologia do Distrito Federal
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Larissa de Brito
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Murilo Macedo
Instituto de Cardiologia do Distrito Federal
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Edilson França Junior
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Adhamys Dias
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Vitor Barzilai
Instituto de Cardiologia do Distrito Federal
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Renato Chaves
Instituto de Cardiologia do Distrito Federal
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Rodrigo Biondi
Instituto de Cardiologia do Distrito Federal
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Guilherme Monte
Instituto de Cardiologia do Distrito Federal
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Claudio da Cunha
Instituto de Cardiologia do Distrito Federal
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Abstract

Background: Infection after cardiovascular surgery is multifactorial. We sought to determine whether the anthropometric profile influence the occurrence of infection after isolated coronary artery bypass grafting (CABG). Methods: Between January 2011 and June 2016, 1,777 consecutive adult patients were submitted to isolated coronary artery bypass grafting. Mean age was 61.7 ± 9.8 years and 1,193 (67.1%) were males. Patients were divided into four groups according to the Body Mass Index (BMI) classification: underweight (BMI<18.5 kg/m2: N=17, 0.9%), normal range (BMI 18.5 – 24.99 kg/m2: N=522, 29.4%), overweight (BMI 25 – 29.99 kg/m2: N=796, 44.8%) and obese (>30 kg/m2: N=430, 24.2%). In-hospital outcomes were compared and independent predictors of infection were obtained through multiple Poisson regression with robust variation. Results: Independent predictors of any infection morbidity were female sex (RR 1.47, P=0.002), age > 60 years (RR 1.85, P<0.0001), cardiopulmonary bypass > 120 minutes (RR 1.89, P=0.0007), preoperative myocardial infarction < 30 days (RR 1.37, P=0.01), diabetes mellitus (RR 1.59, P=0.0003), ejection fraction < 48% (RR 2.12, P<0.0001) and blood transfusion (RR 1.55, P=0.0008). Among other variables, obesity, as well as diabetes mellitus, were independent predictors of superficial and deep sternal wound infection. Conclusions: Other factors rather than the anthropometric profile are more important in determining the occurrence of any infection after CABG. However, surgical site infection has occurred more frequently in obese patients. Appropriate patient selection, control of modifiable factors and application of surgical bundles would minimize this important complication.
18 Dec 2020Submitted to Journal of Cardiac Surgery
19 Dec 2020Assigned to Editor
19 Dec 2020Submission Checks Completed
19 Dec 2020Reviewer(s) Assigned
30 Dec 2020Review(s) Completed, Editorial Evaluation Pending
30 Dec 2020Editorial Decision: Accept